麻楠，女，博士，研究员，硕士生导师。

    2011年毕业于中国药科大学，获学士学位；2016年毕业于中国药科大学药物化学专业（硕博连读，与中国科学院广州生物医药与健康研究院联合培养），获博士学位；同年进入暨南大学从事博士后科研工作；2020年于中国中医科学院青蒿素研究中心进行科研工作；2021年9月经暨南大学高层次人才引进，加入暨南大学药学院。先后从事天然产物全合成、药物化学及化学生物学等科研工作，近年来主要基于分子探针、蛋白质谱等技术手段围绕活性分子开展靶标识别及修饰位点鉴定研究。主持国家及省部级等科学基金项目5项。已在Lancet，J Am Chem Soc，Angew Chem Int Ed Engl，Pharmacol Ther，Nat Prod Rep等国际顶级权威期刊发表学术论著20余篇，累计影响因子432，其中以第一作者/通讯作者（含共同）发表SCI论文13篇。授权发明专利2项。

研究方向：

药物活性分子靶标识别与鉴定；蛋白质组学研究。

教学工作：参与讲授大学基础课程《有机化学》

主持和参与的科研项目：

[1] 国家自然科学基金-面上项目，22377036，2024/01-2027/12。

[2] 国家自然科学基金-青年科学基金项目，81803389，2019/01-2021/12。

[3] 广东省自然科学基金(博士启动)，2018A030310651，2018/05-2021/04。

[4] 中国博士后科学基金，2017M622923，2017/3-2018/12。

[5] 广州市基础与应用基础研究专题，SL2022A04J00501，2023/4-2025/3。

代表性论文：

[1] Ke Cheng, Junyang Qi, Xiaojie Ren, Jie Zhang, Huangxu Li, Hanyue Xiao, Rui Wang, Zhiyang Liu, Lingkuan Meng, Nan Ma*, Hongyan Sun*. Developing Isoxazole as a Native Photo-Cross-Linker for Photoaffinity Labeling and Chemoproteomics. Angew Chem Int Ed Engl. 2022, 21, 61(47).

[2] Nan Ma, Jun Hu, Zhimin Zhang, Wenyan Liu, Minhao Huang, Youlong Fan, Xingfeng Yin, Jiang Wang*, Ke Ding*, Wencai Ye*, Zhengqiu Li*. 2H-Azirine-based Reagents for Chemoselective Bioconjugation at Carboxyl Residues inside Live Cells. J Am Chem Soc., 2020, 142(13): 6051–6059.

[3] Nan Ma, Ziyue Zhang, Fulong Liao, Tingliang Jiang, Youyou Tu*. The birth of artemisinin. Pharmacol Ther., 2020, 216: 107658.

[4] Xiao Chen^#, Yutong Wang^#, Nan Ma^#, Jing Tian, Yurou Shao, Bo Zhu, Yin Kwan Wong, Zhen Liang, Chang Zou, Jigang Wang*. Target identification of natural medicine with chemical proteomics approach: probe synthesis, target fishing and protein identification. Signal Transduct Target Ther., 2020, 5(1): 72.

[5] Hai-Ning Lyu^#, Nan Ma^#, Yuqing Meng^#, Xing Zhang, Yin-Kwan Wong, Chengchao Xu*, Fulong Liao, Tingliang Jiang, Youyou Tu*, Jigang Wang*. Study towards improving artemisinin-based combination therapies. Nat Prod Rep., 2021, 38(7): 1243-1250.

[6] Shengnan Shen^#, Qiwen Liao^#, Ming Lyu^#, Yin-Kwan Wong, Xing Zhang, Jing Zhou*, Nan Ma*, Jigang Wang*. The potential of artemisinins as anti-obesity agents via modulating the immune system. Pharmacol Ther., 2020, 216: 107696.

[7] Yuqing Meng^#, Nan Ma^#, Hai-Ning Lyu^#, Yin Kwan Wong, Xing Zhang, Yongping Zhu, Peng Gao, Peng Sun, Yali Song, Lizhu Lin*, Jigang Wang*. Recent pharmacological advances in the repurposing of artemisinin drugs. Med Res Rev., 2021, 41(6): 3156–3181.

[8] Nan Ma^#, Yiwu Yao^#, Bing-Xin Zhao, Ying Wang, Wen-Cai Ye*, Sheng Jiang*. Total synthesis of securinega alkaloids (-)-norsecurinine, (-)-niruroidine and (-)-flueggine A. Chem. Commun., 2014, 50: 9284–9287. (IF = 5.996)

[9] Dandan Liu^#, Piao Luo^#, Liwei Gu, Qian Zhang, Peng Gao, Yongping Zhu, Xiao Chen, Qiuyan Guo, Junzhe Zhang, Nan Ma*, Jigang Wang*, Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia-reperfusion. J Neuroinflamm., 2021, 18(1): 1–18.

[10] Nan Ma, Zhi-Min Zhang, Jun-Seok Lee, Ke Cheng, Ligen Lin, Dong-Mei Zhang, Piliang Hao*, Ke Ding*, Wen-Cai Ye*, Zhengqiu Li*. Affinity-based Protein Profiling Reveals Cellular Targets of Photoreactive Anticancer Inhibitors. ACS Chem Biol., 2019, 14(12): 2546–2552.

邮箱：nanma0927@jnu.edu.cn