吴振龙,博士,副研究员,硕士生导师。
2017年毕业于暨南大学,获医学博士学位,同年进入暨南大学中西医结合博士后流动站,2018年12月赴伊利诺伊大学芝加哥分校访学,2020年进入暨南大学药学院工作。主要从事中药和天然药物的活性成分研究,先后主持国家自然科学基金面上项目、青年科学基金项目、中国博士后科学基金特别资助项目和广东省自然科学基金面上项目等国家和省部级以上项目5项,并作为课题骨干参与国家重点研发计划项目、国家自然科学基金重点项目及NSFC-广东省政府联合基金重点项目等多项.
在Angewandte Chemie International Edition、Organic Letters、Journal of Organic Chemistry和Journal of Natural Products等国际权威期刊发表研究论文发表SCI论文30余篇;申请中国发明专利3项;参编专著1部。
主要研究方向:
1.中药和天然药物的活性成分研究
2. 天然生物活性分子高效发现策略研究
主持的代表性科研项目:
1.国家自然科学基金面上项目(项目编号:82273822,主持)
2.国家自然科学基金青年科学基金项目(项目编号:81803379,主持)
3.中国博士后科学基金特别资助项目(项目编号:2019T120794,主持)
4. 中国博士后科学基金面上项目(项目编号:2018M633291,主持)
5.广东省基础与应用基础研究基金自然科学基金面上项目(项目编号:2022A1515010010,主持)
代表性论文:
1. Wu, Z. L.#; Zhao, B. X.#; Huang, X. J.; Tang, G. Y.; Shi, L.; Jiang, R. W.; Liu, X.; Wang, Y.*; Ye, W. C.*, Suffrutines A and B: a pair of Z/E isomeric indolizidine alkaloids from the roots of Flueggea suffruticosa. Angew. Chem. Int. Ed. 2014, 53, 5796-5799.
2. He, Q. F.#; Wu, Z. L.#; Li, L.; Sun, W. Y.; Wang, G. Y.; Jiang, R. W.; Hu, L. J.; Shi, L.; He, R. R.; Wang, Y.*; Ye, W. C.* Discovery of Neuritogenic Securinega Alkaloids from Flueggea suffruticosa by a Building Blocks-Based Molecular Network Strategy. Angew. Chem. Int. Ed. 2021, 60, 19609-19613.
3. Wu, Z. L.#; Huang, X. J.#; Hu, L. J.#; Zhang, W. Y.; Xie, Q. J.; Jiang, R. W.; Wang, Y.*; Ye, W. C.*, Absolute configurations and stereochemical inversion mechanism of epimeric Securinega alkaloids from Flueggea suffruticosa. Org. Lett.2020, 22, 3673-3678.
4. Wu, Z. L.#; Huang, X. J.#; Xu, M. T.; Ma, X.; Li, L.; Shi, L.; Wang, W. J.; Jiang, R. W.; Ye, W. C.*; Wang, Y.*, Flueggeacosines A-C, dimeric securinine-type alkaloid analogues with neuronal differentiation activity from Flueggea suffruticosa. Org. Lett. 2018, 20, 7703-7707.
5. He, Q. F.#; Wu, Z. L.#; Huang, X. J.; Zhong, Y. L.; Li, M. M.; Jiang, R. W.; Li, Y. L.; Ye, W. C.*; Wang, Y.*, Cajanusflavanols A-C, three pairs of flavonostilbene enantiomers from Cajanus cajan. Org. Lett. 2018, 20, 876-879.
6. Wu, Z. L.#; Zhang, W. Y.#; Zhong, J. C.; Huang, X. J.; Xu, W.; Chen, M. F.; Weng, S. Q.; Zhang, D. M.; Che, C. T.*; Ye, W. C.*; Wang, Y.*, Angiogenesis-inhibitory piperidine alkaloids from the leaves of Microcos paniculata. J. Nat. Prod. 2022, 85, 375-383.
7. Liu, H.#; Wu, Z. L.#; Huang, X. J.; Peng, Y.; Huang, X.; Shi, L.; Wang, Y.*; Ye, W. C.*, Evaluation of diarylheptanoid-terpene adduct enantiomers from Alpinia officinarum for neuroprotective activities. J. Nat. Prod.2018, 81, 162-170.
8. He, Q. F.#; Wu, Z. L.#; Huang, X. J.; Xia, T. Q.; Tang, G.; Tang, W.; Shi, L.; Ye, W. C.*; Wang, Y.*, Cajanusoids A-D, unusual atropisomeric stilbene dimers with PTP1B inhibitory activities form the leaves of Cajanus cajan. J.Org. Chem. 2021, 86, 5870-5882.
9. Zhang, J. Y.#; Liu, F.#; Jin, Q; Li, X. Y.; Zhan, Q.; Chen, M.; Wang, S.; Wu, Z. L.*; Ye, W. C.*; Wang, L.* Discovery of unusual phloroglucinol–triterpenoid adducts from Leptospermum scoparium and Xanthostemon chrysanthus by building blocks-based molecular networking. Chin. Chem. Lett. 2023, 108881.
10.Tan, L. X.#; Xia, T. Q.#; He, Q. F.; Tang, W.; Huang, X. J.; Song, Q. Y.; Li, Y. L.; Ye, W. C.*; Wang, Y.*; Wu, Z. L.* Stilbenes from the leaves of Cajanus cajan and their in vitro anti-inflammatory activities. Fitoterapia 2022, 160, 105229.
邮箱:zhenlongwu@jnu.edu.cn