1. ENO2-derived phosphoenolpyruvate functions as an endogenous inhibitor of HDAC1 to confer resistance to antiangiogenic therapy
Nat Metab, 2023; 10.1038/s42255-023-00883-y.
Wang CR#, Huang MH#, Lin YN#, Zhang YM, Pan JH, Jiang C, Cheng MJ, Li SR, He WZ, Li ZQ, Tu ZC, Fan J, Zeng HH, Lin JH, Wang YJ, Yao N, Liu TZ, Qi Q, Liu XN, Zhang ZM, Chen MF*, Xia LP*, Zhang DM*, Ye WC*
2. Novel TCF21high pericyte subpopulation promotes colorectal cancer metastasis by remodeling perivascular matrix
Gut, 2023;72(4): 710-721.
Li XB#, Pan JH#, Liu TZ#, Yin WQ, Miao Q, Zhao Z, Gao YF, Zheng W, Li H, Deng R, Huang DD, Qiu SH, Zhang YR, Qi Q, Deng LJ, Huang MH, Tang Ming-Kuen Patrick, Cao YH*, Chen MF*, Ye WC*, Zhang DM*
3. Targeting FAPα-expressing hepatic stellate cells overcomes resistance to anti-angiogenics in colorectal cancer liver metastasis models
J Clin Invest,2022;132(19):e157399.
Qi M#, Fan SR#, Huang MH#, Pan JH, Li Y, Miao Q, Lyu WY, Li XB, Deng LJ, Qiu SH, Liu TZ, Deng WQ, Chu XD, Jiang C, He WZ, Xia LP, Yang YL, Hong J, Qi Q, Yin WQ, Liu XN, Shi CZ, Chen MF*, Ye WC*, Zhang DM*.
4. Discovery of Neuritogenic Securinega Alkaloids from Flueggea suffruticosa by a Building Blocks-Based Molecular Network Strategy
Angew Chem Int Ed Engl., 2021, 60 (36): 19609-19613.
He QF#, Wu ZL#, Li LR, Sun WY, Wang GY, Jiang RW, Hu LJ, Shi L, He RR, Wang Y*, Ye WC*.
5. Myofibroblast-Specific Msi2 Knockout Inhibits Hepatocellular Carcinoma Progression in a Mouse Model.
Hepatology, 2021, 74, 458–473.
Qu C#, He L#, Yao N, Li JY, Jiang YC, Li BK, Peng S, Hu KP, Chen D, Chen G, Huang W, Cao MR, Fan J, Yuan YF, Ye WC*, Hong J*.
6. Perivascular cell-derived extracellular vesicles stimulate colorectal cancer revascularization after withdrawal of antiangiogenic drugs.
J Extracell Vesicles.2021;10: e12096
Huang MH#, Chen MF#, Qi M, Ye GN, Pan JH, Shi CZ, Yang YL, Zhao LY, Mo XK, Zhang YR, Li Y, Zhong JC, Lu WJ, Li XB, Zhang JY, Lin JR, Luo LP, Liu TZ, Patrick MK Tang, Hong A, Cao YH*, Ye WC*, Zhang DM*.
7. Asymmetric Total Synthesis of Bufospirostenin A
J. Am. Chem. Soc, 2020, 142: 12602–12607.
Cheng MJ, Zhong LP, Gu CC, Zhu XJ, Chen B, Liu JS, Wang L*, Ye WC*, Li CC*
8. 2H-Azirine-Based Reagents for Chemoselective Bioconjugation at Carboxyl Residues Inside Live Cells.
J. Am. Chem. Soc,2020, 142: 6051-6059.
Ma N, Hu J, Zhang ZM, Liu W, Huang M, Fan Y, Yin X, Wang J, Ding K*, Ye W*, Li Z*.
9. Suffrutines A and B: a pair of Z/E isomeric indolizidine alkaloids from the roots of Flueggea suffruticosa
Angew Chem Int Ed Engl., 2014, 53 (23): 5796-5799
Wu ZL#, Zhao BX#, Huang XJ, Tang GY, Shi L, Jiang RW, Liu X, Wang Y*, Ye WC*
10. Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agents
The Journal of Clinical Investigation, 2017,127(10):3689-3701,
Chen MF#, Lei XP#, Shi CZ, Huang MH, Li XB, Wu BJ, Li ZQ, Han WL, Du B, Hu JY, Nie QL, Mai WQ, Ma N, Xu NH, Zhang XY, Fan CL, Hong AH, Xia MH, Luo LP, Ma AD, Li HS, Yu Q, Chen HR*, Zhang DM*, Ye WC*.
11. Autism-like social deficit generated by Dock4 deficiency is rescued by restoration of Rac1 activity and NMDA receptor function
Mol Psychiatry. 2019Aug 6. doi: 10.1038/s41380-019-0472-7.
Guo D#, Peng Y#, Wang L, Sun X, Wang X, Liang C, Yang X, Li S, Xu J, Ye WC*, Jiang B*, Shi L*.
1. Chen M#, Cao J-Q#, Ang S#, Zeng T-N, Li N-P, Yang T-J, Liu J-S, Wu Y, Ye W-C*, Wang L*. Eugenunilones A-H: Rearranged Sesquiterpenoids from Eugenia Uniflora. Organic Chemistry Frontiers, 2022, 9, 667–675.
2. Huang M#, Liu M#, Huang D, Ma Y, Ye G, Wen Q, Li Y, Deng L, Qi Q, Liu T, Liu X, Chen M*, Ye W*, Zhang D*. Tumor Perivascular Cell-Derived Extracellular Vesicles Promote Angiogenesis via the Gas6/Axl Pathway. Cancer Letters, 2022, 524, 131–143.
3. Wu Z-L#, Zhang W-Y# , Zhong J-C, Huang X-J, Xu W, Chen M-F, Weng S-Q, Zhang D-M, Che C-T*, Ye W-C*, Wang Y*. Angiogenesis-Inhibitory Piperidine Alkaloids from the Leaves of Microcos Paniculata. Journal of Natural Products, 2022, 85 (2), 375–383.
2021年:
4. Guo D#, Peng Y#, Wang L, Sun X, Wang X, Liang C, Yang X, Li S, Xu J, Ye W-C*, Jiang B*, Shi L*. Autism-like Social Deficit Generated by Dock4 Deficiency Is Rescued by Restoration of Rac1 Activity and NMDA Receptor Function. Molecular Psychiatry, 2021, 26, 1505–1519.
5. Ye G#, Huang M#, Li Y, Ouyang J, Chen M, Wen Q, Li X, Zeng H, Long P, Fan Z, Yin J*, Ye W*, Zhang D*. The FAPα-Activated Prodrug Z-GP-DAVLBH Inhibits the Growth and Pulmonary Metastasis of Osteosarcoma Cells by Suppressing the AXL Pathway. Acta Pharmaceutica Sinica B, 2021, doi:10.1016/j.apsb.2021.08.015.
6. Li X#, Chen M#, Lu W, Tang J, Deng L, Wen Q, Huang M, Deng R, Ye G, Ye W*, Zhang D*. Targeting FAPα-expressing tumor-associated mesenchymal stromal cells inhibits triple-negative breast cancer pulmonary metastasis. Cancer Letters,2021,503, 32-42.
7.Huang M#, Liu M#, Huang D#, Ma Y, Ye G, Wen Q, Li Y, Deng L, Qi Q, Liu T, Liu X, Chen M*, Ye W*, Zhang D*. Tumor perivascular cell-derived extracellular vesicles promote angiogenesis via the Gas6/Axl Pathway. Cancer Letters, 2022, 524, 131–143.
8. Deng L-M#, Hu L-J#, Bai Y-T-Z, Wang J, Qin G-Q, Song Q-Y, Su J-C, Huang X-J, Jiang R-W, Tang W, Li Y-L, Li C-C, Ye W-C*, Wang Y*. Rhodomentosones A and B: Two Pairs of Enantiomeric Phloroglucinol Trimers from Rhodomyrtus tomentosa and Their Asymmetric Biomimetic Synthesis. Organic Letters, 2021, 23 (11), 4499–4504.
9. Gu J-H#, Zhang W#, Cai W-Y, Fu X-X, Zhou H-L, Li N-P, Tian H-Y, Liu J-S*, Ye W-C*, Wang L*. Gelserancines A-E, Monoterpenoid Indole Alkaloids with Unusual Skeletons from Gelsemium elegans, Organic Chemistry Frontiers, 2021, 8, 1918–1925.
10.Li N-P#, Liu J-S#, Liu J-W, Tian H-Y, Zhou H-L, Zheng Y-R, Huang X-J, Cao J-Q, Ye W-C*, Wang L*. Monoterpenoid indole alkaloids from the fruits of Gelsemium elegans and their anti-inflammatory activities. Bioorganic Chemistry, 2021, 107, 104624.
11.He Q-F#, Wu Z-L#, Huang X-J, Xia T-Q, Tang G, Tang W, Shi L, Ye W-C*, Wang Y*. Cajanusoids A–D, unusual atropisomeric stilbene dimers with PTP1B inhibitory activities from the leaves of Cajanus cajan. Journal of Organic Chemistry, 2021, 86 (8), 5870–5882.
12.Yao N#, Wang C-R#, Liu M-Q, Li Y-J, Chen W-M, Li Z-Q, Qi Q, Lu J-J, Fan C-L, Chen M-F, Qi M, Li X-B, Hong J, Zhang D-M*, Ye W-C*. Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth. Signal Transduction and Targeted Therapy,2020, 5, 214.
13.Wu Z-L#, Huang X-J#, Hu L-J#, Zhang W-Y, Xie Q-J, Jiang R-W, Wang Y*, Ye W-C*. Absolute Configurations and Stereochemical Inversion Mechanism of Epimeric Securinega Alkaloids from Flueggea suffruticosa. Organic Letters, 2020, 22: 3673−3678.
14.Gu JH#, Wang WJ#, Chen JZ, Liu JS, Li NP, Cheng MJ, Hu LJ, Li CC*, Ye WC*, Wang Lei*. Leptosperols A and B, Two Cinnamoylphloroglucinol- Sesquiterpenoid Hybrids from Leptospermum scoparium: Structural Elucidation and Biomimetic Synthesis. Organic Letters, 2020, 22(5): 1796−1800.
15.Zhang J#, Yuan M-F#, Li S-T#, Sang C-C, Chen M-F, Ao Y-L, Li Z-W, Xie J, Ye W-C*, Zhang X-Q*. Hunzeylanines A-E, Five Bisindole Alkaloids Tethered with a Methylene Group from the Roots of Hunteria zeylanica. The Journal of Organic Chemistry,2020, 85, 10884-10890.
16. Cheng MJ#, Yang XY#, Cao JQ, Liu C, Zhong LP, Wang Y, You XF, Li CC*, Wang L*, Ye WC*. Isolation, Structure Elucidation, and Total Synthesis of Myrtuspirone A from Myrtus communis. Organic Letters, 2019, 21 (6): 1583-1587.
17. Song J-G#, Su J-C#, Song Q-Y, Huang R-L, Tang W, Hu L-J, Huang X-J, Jiang R-W, Li Y-L, Ye W-C*, Wang Y*. Cleistocaltones A and B, Antiviral Phloroglucinol-Terpenoid Adducts from Cleistocalyx operculatus. Organic Letters, 2019, 21(23): 9579-9583.
18. Yao N#, Wang C#, Hu N, Li Y, Liu M, Lei Y, Chen M, Chen L, Chen C, Lan P, Chen W, Chen Z, Fu D, Ye W, Zhang D*. Inhibition of PINK1/Parkin-dependent mitophagy sensitizes multidrug-resistant cancer cells to B5G1, a new betulinic acid analog. Cell Death and Disease, 2019, 10(3): 232.
19.Zhang J#, Liu M#, Huang M, Chen M, Zhang D, Luo L, Ye G, Deng L, Peng Y, Wu X, Liu G, Ye W*, Zhang D*. Ginsenoside F1 promotes angiogenesis by activating the IGF-1/IGF1R pathway. Pharmacological Research, 2019, 144: 292-305.
20.Zhang J#, Liu Z-W#, Ao Y-L, Hu L-J, Wei C-J, Zhang Q-H, Yuan M-F, Wang Y, Zhang Q-W*, Ye W-C*, Zhang X-Q*. Hunterines A–C, Three Unusual Monoterpenoid Indole Alkaloids from Hunteria zeylanica. The Journal of Organic Chemistry, 2019, 84(22): 14892-14897.
21.Liu F#, Tian H-Y#, Huang X-L, Wang W-J, Li N-P, He J, Ye W-C*, Wang L*. Xanthchrysones A-C: Rearranged Phenylpropanoyl-Phloroglucinol Dimers with Unusual Skeletons from Xanthostemon chrysanthus. The Journal of Organic Chemistry 2019, 84, 15355-15361.
22. Cheng MJ, Cao JQ, Yang XY, Zhong LP, Hu LJ, Lu X, Hou BL, Hu YJ, Wang Y, You XF, Wang L*, Ye WC*, Li CC*. Catalytic Asymmetric Total Syntheses of Myrtucommuacetalone, Myrtucommuacetalone B and Callistrilones A, C, D, E. Chemical Science, 2018, 8(6): 1488-1495.
23. Lei XP#, Chen MF#, Huang MH, Li XB, Shi CZ, Zhang D, Luo LP, Zhang YW, Ma N, Chen HR, Liang HF, Ye WC*, Zhang DM*. Desacetylvinblastine Monohydrazide Disrupts Tumor Vessels by Promoting VE-cadherin Internalization. Theranostics, 2018, 8(2): 384-398.
24. Wu ZL#, Huang XJ#, Xu MT, Ma X, Li L, Shi L, Wang WJ, Jiang RW, Ye WC*, Wang Y*. Flueggeacosines A–C, Dimeric Securinine-Type Alkaloid Analogues with Neuronal Differentiation Activity from Flueggea suffruticosa. Organic Letters, 2018, 20(23): 7703−7707.
25. He QF#, Wu ZL#, Huang XJ, Zhong YL, Li MM, Jiang RW, Li YL, Ye WC*, Wang Y*. Cajanusflavanols A-C, Three Pairs of Flavonostilbene Enantiomers from Cajanus cajan. Organic Letters, 2018, 20(3): 876-879.
26. Zhang YB#, Yang L#, Luo D, Chen NH, Wu ZN, Ye WC*, Li YL*, Wang GC*. Sophalines E-I, Five Quinolizidine-Based Alkaloids with Antiviral Activities against the Hepatitis B Virus from the Seeds of Sophora alopecuroides. Organic Letters, 2018, 20(18): 5942-5946.
27. Lei XP#, Chen MF#, Li XB, Huang MH, Nie QL, Ma N, Chen HR, Xu NH, Ye WC*, Zhang DM*. A vascular disrupting agent overcomes tumor multidrug resistance by skewing macrophage polarity toward the M1 phenotype. Cancer letters, 2018, 418: 239-249.
28. Su JC#, Wang S#, Cheng W, Huang XJ, Li MM, Jiang RW, Li YL, Wang L, Ye WC*, Wang Y*. Phloroglucinol Derivatives with Unusual Skeletons from Cleistocalyx operculatus and Their in Vitro Antiviral Activity. Journal of Organic Chemistry, 2018, 83(15): 8522-8532.
29. Liu ZW#, Zhang J#, Li ST, Liu MQ, Huang XJ, Ao YL, Fan CL, Zhang DM, Zhang QW, Ye WC*, Zhang XQ*. Ervadivamines A and B, Two Unusual Trimeric Monoterpenoid Indole Alkaloids from Ervatamia divaricata. The Journal of Organic Chemistry, 2018, 83(17): 10613−10618.
30. Li NP#, Liu M#, Huang XJ, Gong XY, Zhang W, Cheng MJ, Ye WC*, Wang L*. Gelsecorydines A-E, Five Gelsedine-Corynanthe-Type Bisindole Alkaloids from the Fruits of Gelsemium elegans. The Journal of Organic Chemistry, 2018, 83(10): 5707-5714.
2017年:
31. Zhang W#, Xu W#, Wang GY, Gong XY, Li NP, Wang L*, Ye WC*. Gelsekoumidines A and B: Two Pairs of Atropisomeric Bisindole Alkaloids from the Roots of Gelsemium elegans. Organic Letters, 2017, 19(19): 5194-5197.
32. Zhang YB#, Zhang XL#, Chen NH, Wu ZN, Ye WC*, Li YL*, Wang GC*. Four Matrine-Based Alkaloids with Antiviral Activities against HBV from the Seeds of Sophora alopecuroides. Organic Letters, 2017, 19(2): 424-427.
33. Deng LJ#, Wang LH#, Peng CK, Li YB, Huang MH, Chen MF, Lei XP, Qi M, Cen Y, Ye WC*, Zhang DM*, Chen WM*. Fibroblast Activation Protein alpha Activated Tripeptide Bufadienolide Antitumor Prodrug with Reduced Cardiotoxicity. Journal of Medicinal Chemistry, 2017, 60(13): 5320-5333.
34. Sun HY#, Huang MH#, Yao N#, Hu JY, Li YJ, Chen LP, Hu N, Ye WC, Tai WCS, Zhang DM*, Chen SB*. The cycloartane triterpenoid ADCX impairs autophagic degradation through Akt overactivation and promotes apoptotic cell death in multidrug-resistant HepG2/ADM cells. Biochemical Pharmacology, 2017, 146: 87-100.
35. Chen LP#, Mai WQ#, Chen MF, Hu JY, Zhuo ZJ, Lei XP, Deng LJ, Liu JS, Yao N, Huang MH, Peng YH, Ye WC* Zhang DM*. Arenobufagin inhibits prostate cancer epithelial-mesenchymal transition and metastasis by down-regulating beta-catenin. Pharmacological Research, 2017, 123: 130-142.